H1-7 (histone H1 phosphorylation site), PKA SubstrateA synthetic peptide PKA substrate

H1-7 (histone H1 phosphorylation site), PKA Substrate (CAS 65189-70-0)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 100ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: Histone H1 phosphorylation site; PKA substrate; Arg-Arg-Lys-Ala-Ser-Gly-Pro; RRKASGP
Application: A synthetic peptide PKA substrate
CAS Number: 65189-70-0
Purity: >97%
Molecular Weight: 770.9
Molecular Formula: C31H58N14O9
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

H1-7 (histone H1 phosphorylation site), PKA Substrate is a synthetic peptide that acts as a pseudo substrate for PKA (cAMP-dependent protein kinase). This peptide was derived from the calf thymus histone H1 amino acid sequence about serine-38 and was used to research the reaction mechanism of the PKA catalytic subunit. H1-7 exhibits a greater absolute catalytic rate of phosphorylation than H1, an absolute Michaelis constant 40-fold greater than whole histone H1, but exhibits less affinity. Peptide sequence of H1-7: RRKASGP.


1. Pomerantz, A.H., et al. 1977. Proc. Natl. Acad. Sci. U.S.A. 74: 4261-4265. PMID: 200911

Usage :
•The peptide is to be dissolved in distilled or preferably sterile water first. The concentration should be high enough to allow addition of buffer after the product is dissolved completely.

•If necessary dilute acetic acid or ammonium hydroxide, app. 1%, can be added to help solubilize the peptide. In those rare cases where solubilization is still not achieved, the solution may be sonicated briefly (up to 10 min. temperature should not rise over 30-40° C).

•In order to avoid serious solubility problems, buffer or saline should be added after the peptide is fully in solution.

•For storage the pH range of the peptide solution is preferably in the range of 5.0 to 7.0 and should be in a freezer at -20C.
Physical State :
Sequence :
Solubility :
Soluble in water.
Storage :
Store at -20° C
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.67
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 78ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 32ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.