Guanosine 5prime-triphosphate dilithium saltA stable 5'-GTP preparation

Guanosine 5′-triphosphate dilithium salt (CAS 85737-04-8 (non-salt))

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Application: A stable 5'-GTP preparation
CAS Number: 85737-04-8 (non-salt)
Purity: >97%
Molecular Weight: 533.1
Molecular Formula: C10H12N5O14P32Li
* Refer to Certificate of Analysis for lot specific data (including water content).
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Guanosine 5'-triphosphate dilithium salt is prepared by enzymatic phosphorylation of 5'-GMP. This salt form is much more stable than the sodium salt.


References

Gutkind, J.S., Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17, 1331-1342, (1998) Dhanasekaran, N., et al., Regulation of cell proliferation by G proteins. Oncogene 17, 1383-1394, (1998) Hepler, J.R., and Gilman, A.G., G proteins. Trends Biochem. Sci. 17, 383-387, (1992) Gomez, J., et al., Dual role of Ras and Rho proteins: at the cutting edge of life and death. Immunol. Cell Biol. 76, 125-134, (1998) Lacal, J.C., Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling. FEBS Lett. 410, 73-77, (1997) Schimmoller, F., et al., Rab GTPases, directors of vesicle docking. J. Biol. Chem. 273, 22161-22164, (1998) Woodman, P., Vesicle transport: more work for the Rabs?. Curr. Biol. 8, R199-R201, (1998)

Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at -20° C
Refractive Index :
n20D ~1.94 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44147102
MDL Number :
MFCD00672159
EC Number :
279-263-0
SMILES :
[Li+].[Li+].C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)O)O)O)NC(=NC2=O)N

Download SDS (MSDS)

Certificate of Analysis

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