Guanabenz acetate is an α2A-AR adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand. Guanabenz acetate is an activator of alpha2B-AR (α2b-adrenergic receptor) and alpha2C-AR (α2c-adrenergic receptor).
1. Holmes, B., et al. 1983. Drugs. 26: 212-229. 2. Michel, M.C. and Insel, P.A. 1989. Trends Pharmacol Sci. 10: 342-344. 3. Evans, R.G. and Anderson, W.P. 1995. Br. J. Pharmacol. 116: 1557-1570.
Soluble in DMSO (75 mM), water (11 mg/ml at 25° C), alcohol (50 mg/ml at 25° C), chloroform (0.6 mg/ml at 25° C), and propylene glycol (100 mg/ml at 25° C).
Store at room temperature
192.5° C (dec.)
405.7° C at 760 mmHg (tautomer)
n20D ~1.65 (Predicted)
Plasmodium falciparum: IC50 = 3.16 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
bvseo_sdk, java_sdk, bvseo-3.2.0
CLOUD, getContent, 64ms
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Inhibitor of eIF2α dephosphorylationEfficient for inhibiting eIF2α (α-subunit of eukaryotic initiation factor 2) dephosphorylation in the parasitic protist Toxoplasma.
Date published: 2017-09-05
Rated 5 out of
VieiraVieira, FG. et al. (PubMed 26288094) reported that Guanabenz treatment accelerated disease in a mutant SOD1 mouse model of ALS. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.