Anti-gremlin-1 Antibody (C-7) is a mouse monoclonal IgG2b κ gremlin-1 antibody, cited in 4 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 32-61 near the N-terminus of gremlin-1 of human origin
Anti-gremlin-1 Antibody (C-7) is recommended for detection of gremlin-1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-gremlin-1 Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of gremlin-1 (C-7): sc-515877.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for gremlin-1 Antibody (C-7) for WB applications. These reagents are now offered in bundles with gremlin-1 Antibody (C-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
gremlin-1 Antibody (C-7) is a high quality monoclonal gremlin-1 antibody (also designated DAN Family BMP Antagonist antibody, Cysteine Knot Superfamily 1 BMP Antagonist 1 antibody, DAND2 antibody, DRM antibody, Down-Regulated In Mos-Transformed Cells Protein antibody, Cell Proliferation-Inducing Gene 2 Protein antibody, Hereditary Mixed Polyposis Syndrome antibody, Colorectal Adenoma And Carcinoma 1 antibody, DAN Domain Family Member 2 antibody, CKTSF1B1 antibody, IHG-2 antibody, HMPS antibody, Gremlin 1 Cysteine Knot Superfamily Homolog antibody, Increased In High Glucose Protein 2 antibody, Increased In High Glucose-2 antibody, Gremlin antibody, CRAC1 antibody, CRCS4 antibody, HMPS1 antibody, MPSH antibody, or PIG2 antibody) suitable for the detection of the gremlin-1 protein of mouse, rat and human origin. gremlin-1 Antibody (C-7) is available as both the non-conjugated anti-gremlin-1 antibody form, as well as multiple conjugated forms of anti-gremlin-1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The gremlin protein family contains antagonists of bone morphogenetic protein (BMP) signaling that are expressed in the neural crest. All family members are secreted proteins that act as BMP antagonists in embryonic explants and are expressed in the proximal airway epithelium of the lung during embryonic development. Gremlin-1 is required for early limb outgrowth and patterning in the FGF4-SHH feedback loop, while gremlin-2 binds and blocks the activity of BMP-2 and BMP-4. The dorsaling factor gremlin belongs to a novel gene family that includes the head-inducing factor Cerberus and the tumor suppressor DAN. Additionally, secreted gremlin relays the sonic hedgehog signal from the polarizing region to the apical ectodermal ridge.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences