Granzyme B inhibitor InhibitorA weak inhibitor of Granzyme B

Granzyme B inhibitor Inhibitor

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Synonym: Z-Ala-Ala-Asp-CH2Cl
Application: A weak inhibitor of Granzyme B
Purity: ≥95%
Molecular Weight: 441.9
Molecular Formula: C19H24ClN3O7
* Refer to Certificate of Analysis for lot specific data (including water content).
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Granzyme B inhibitor is a weak inhibitor of murine and human Granzyme B. It also inhibits the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2, which is a rat lymphocyte granule protease homologous to Granzyme B (ID50 = 300 nM).

Physical State :
Sequence :
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

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Granzyme B inhibitor Inhibitor  Product Citations

See how others have used Granzyme B inhibitor Inhibitor. Click on the entry to view the PubMed entry .

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PMID: # 31633216  Eur. J. Immunol. 49: 1457-1973.

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Asked by: liya
感谢您的提问。SC-3087为颗粒酶B的不可逆、细胞渗透型抑制剂。更多信息请参考以下文献: Gong, B., et al. 1999. Cell Growth Different. 10, 491. Shi, L., et al. 1992. J. Exp. Med. 176, 1521. Odake, S., et al. 1991. Biochemistry 30, 2217. Thank you for your question. SC-3087 is an irreversible, cell-permeable inhibitor of granzyme B. Above are some references that may help.
Answered by: Technical Support 12
Date published: 2016-10-19
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