Gramicidin A is a naturally occurring antibiotic that acts as an ion channel-forming pentadecapeptide. Bacillus brevis produces Gramicidin and is an effective antibiotic against gram-positive organisms. Gramicidin can be used to study membrane channels because of its cation-selective, single-filing pore and has been used as a model to study ion channel proteins, and acylation of membrane proteins. The Gramicidin A channel has demonstrated to be permeable to small monovalent cations, protons, and water but impermeable to divalent cations and anions.
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See how others have used Gramicidin A. Click on the entry to view the PubMed entry .
PMID: # 30746686 2019. J. Cell. Physiol.
PMID: # 7684267 Seoh, SA. et al. 1993. Biophys. J. 64: 1017-1028.
PMID: # 19871101 Dubos, RJ. et al. 1941. J. Exp. Med. 73: 629-640.
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