GM2/GD2 Synthase Antibody (C-5) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 1-180 mapping at the N-terminus of GM2 of human origin
GM2/GD2 Synthase Antibody (C-5) is recommended for detection of GM2/GD2 synthase of mouse, rat and human origin by WB, IP, IF and ELISA
GM2/GD2 Synthase Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of GM2/GD2 Synthase (C-5): sc-376505.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
GM2/GD2 synthase is a 533 amino acid protein encoded by the human gene B4GALNT1. The GM2 and GD2 gangliosides are sialic acid-containing glyco-sphingolipids that play a role in signal transduction and cell-cell recognition. GM2/GD2 synthase is expressed abundantly in normal brain tissue of vertebrates. It contains a single 18 amino acid hydrophobic segment near the amino-terminus flanked by basic residues. GM2/GD2 synthase primarily controls the balance between expression of simple and complex gangliosides at the cell surface. The ganglioside GD2 is expressed using GM2/GD2 synthase in almost all neuroblastomas (NBs) as well as other neuroectoderm-derived tumor cells, such as malignant melanoma, adult T cell leukemia and some colon and gastric cancers. GM2/GD2 synthase is a useful marker for NBs, and may aid in evaluating adjuvant treatment efficacy in neuroblastoma with prognostic potential.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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