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Geranyl bromide (CAS 6138-90-5)

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Alternate Names:
trans-1-Bromo-3,7-dimethyl-2,6-octadiene
Application:
Geranyl bromide is a useful chemical for synthesis of 3,7-dihydroxyflavone derivatives and baicalein
CAS Number:
6138-90-5
Purity:
≥95%
Molecular Weight:
217.15
Molecular Formula:
C10H17Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Geranyl bromide is used in organic chemistry research, particularly in the synthesis of more complex organic molecules. It acts as an alkylating agent, providing a geranyl group that can be attached to other molecules, thereby altering their properties and functions. Researchers employ geranyl bromide in the study of terpenes and terpenoids, which are important in the development of natural product chemistry and the synthesis of pharmaceuticals and fragrances. The compound is also utilized to investigate reaction mechanisms, especially those involving carbocation intermediates, which are pivotal in understanding synthetic pathways. Additionally, geranyl bromide is useful in materials science for creating organic compounds that have potential applications in new material formulations, contributing to advances in both functional and structural material development.


Geranyl bromide (CAS 6138-90-5) References

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  2. The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein.  |  Maitrejean, M., et al. 2000. Bioorg Med Chem Lett. 10: 157-60. PMID: 10673101
  3. Synthesis of geranyl S-thiolodiphosphate. A new alternative substrate/inhibitor for prenyltransferases.  |  Phan, RM. and Poulter, CD. 2000. Org Lett. 2: 2287-9. PMID: 10930265
  4. Synthesis and anti-inflammatory activity of natural and semisynthetic geranyloxycoumarins.  |  Curini, M., et al. 2004. Bioorg Med Chem Lett. 14: 2241-3. PMID: 15081016
  5. Synthesis and biological activity of isoprenoid bisphosphonates.  |  Shull, LW., et al. 2006. Bioorg Med Chem. 14: 4130-6. PMID: 16517172
  6. Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis.  |  Neves, MP., et al. 2011. Eur J Med Chem. 46: 2562-74. PMID: 21496973
  7. Palladium-catalyzed allyl cross-coupling reactions with in situ generated organoindium reagents.  |  Lee, K., et al. 2011. Chem Asian J. 6: 2147-57. PMID: 21538904
  8. Synthesis of isoprenoid bisphosphonate ethers through C-P bond formations: Potential inhibitors of geranylgeranyl diphosphate synthase.  |  Zhou, X., et al. 2014. Beilstein J Org Chem. 10: 1645-50. PMID: 25161722
  9. A concise total synthesis and PPAR activation activity of hericerin from Hericium erinaceum.  |  Zheng, Z., et al. 2020. J Antibiot (Tokyo). 73: 646-649. PMID: 32269298
  10. An improved method for 14C-labelling of farnesylacetic acid and its geranyl ester.  |  Nishioka, K., et al. 1988. Radioisotopes. 37: 133-9. PMID: 3387600
  11. Terpene compounds as drugs. VI. Acyclic mono- and sesquiterpene thiocyanates and isothiocyanates.  |  Pala, G., et al. 1969. J Med Chem. 12: 725-6. PMID: 4307375
  12. Synthesis of Geranyloxycoumarin Derivatives under Mild Conditions Using Cs2CO3  |  Sumi HWANG Eonjoo ROH and. 28.02.2022. Journal of the Turkish Chemical Society Section A: Chemistry. Volume: 9 Issue: 1,: 57 - 66,.
  13. 2-(Tributylstannyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-indole: Synthesis and use as a 1H-indol-2-yl-anion equivalent  |  Giovanni Palmisano, Marco Santagostino. September 1993. Helvetica Chimica Acta. Volume76, Issue6 22: Pages 2356-2366.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Geranyl bromide, 5 g

sc-250050
5 g
$53.00

Geranyl bromide, 25 g

sc-250050A
25 g
$202.00