Ganglioside GM3 sodium salt is the major ganglioside of the extra-nervous system. Inhibits growth of epidermal cells. GM3 is known as the main extraneuronal ganglioside. Ganglioside GM3 sodium salt is useful as a substrate for sialidase, after this treatment yields the corresponding lactosylceramide. Also known as the co-receptor of cell growth factor (EGF and FGF). Antibodies to GM3 inhibit 3T3 and NIL cell growth.
1. Bremer, E.G., et al. 1986. J. Biol. Chem. 261: 2434-2440. PMID: 2418024
Soluble in water (partly), and chloroform:methanol (2:1).
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Asked by: sangmi
죄송합니다.우리 웹에서 구조 정보 없습니다.분자식:C59H107N2O21•Na.
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CaughlinCaughlin, S. et al. (PubMed 26086081) found increased expression of simple Ganglioside species GM2 and GM3 in a combined rat model of A toxicity and stroke. -SCBT Publication Review
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