Ganglioside GM1, Asialo is a product that is a highly purified sialic acid-containing glycolipid; a component of the cell plasma membrane known to modulate cell signal transduction. Ganglioside GM1, Asialo can be a useful marker of cell types and antigens. It has been reported to spontaneously form small homogeneous vesicles without any protein templating. In response to ganglioside GM1, it has been reported that T cells from Guillain-Barrε syndrome patients produce interferon-gamma, a cytokine that is critical for the formation of adaptive immunity against bacterial or viral infections.
1. Schengrund, C.L., et al. 1989. J. Biol. Chem. 264: 13233-13237. PMID: 2666416 2. Schroder, K., et al. 2004. J. Leukoc. Biol. 75: 163-189. PMID: 14525967 3. Chebukati, J.N., et al. 2010. Biochem. Biophys. Res. Commun. 394: 509-514. PMID: 20206128 4. McCombe, P.A., et al. 2010. J Clin Neurosci. 17: 537-538. PMID: 20093028
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
hello is this asialo or sialic acid-containing ganglioside?
Asked by: pank007
Thank you for your question. Ganglioside GM1, Asialo: sc-202625 has an alternate name that is Asialoganglioside-GM1. If this does not answer your question, please contact our Technical Service Department for more information. Please call us toll-free at (800) 457-3801 option 2, e-mail <firstname.lastname@example.org>, or use the live chat on our website.
Rated 5 out of
McCombeMcCombe, PA. et al. (PubMed 20093028) reported that T cells from subjects with Guillain-Barr syndrome produce interferon-gamma in response to stimulation with Ganglioside GM1, Asialo. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.