Ganglioside GD3, Disialo, Diammonium Salt has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Antibodies to GD3 can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. Reported to disrupt mitochodrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. A protein kinase C inhibitor.
DeMaria, R., et al. 1997. Science 277, 1652.
Soluble in Chloroform:Methanol (2:1), and water (1 mg/ml).
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.