γ-Secretase Inhibitor is an inhibitor of γ-secretase, a protease that cleaves the amyloid precursor protein (APP). The inhibition of the γ-secretase enzyme is being researched for possible preventative properties towards Alzheimer's disease.
Skovronsky, D.M., et al. 2000. Biochemistry 39, 810. Hartmann, T., et al. 1997. Nat. Med. 3, 1016.
Z-Leu-Leu-Nle-CHO (Nle = Norleucine)
Soluble in 50% acetic acid, and DMSO (10 mg/ml).
Store at -20° C
686.55° C at 760 mmHg (Predicted)
1.07 g/cm3 (Predicted)
n20D 1.51 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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