Galanthamine Hydrobromide is a competitive and reversible AChE (acetylcholinesterase) inhibitor, which displays allosteric potentiating effects at nicotinic receptors. In addition, Galanthamine Hydrobromide affects cholinergic transmission and the release of neurotransmitters such as monoamines, glutamate, and γ-aminobutyric acid (GABA). As a result of its inhibitory effects on acetylcholinesterase, Galanthamine Hydrobromide increases the concentration of acetylcholine in the brain.
1. Yonkov, D.I. and Georgiev, V.P. 1990. Neuropeptides. 16: 157-162. PMID: 1964494 2. Thomsen, T., et al. 1991. Eur J Clin Chem Clin Biochem. 29: 487-492. PMID: 1954303 3. Dal-Bianco, P., et al. 1991. J. Neural Transm. Suppl. 33 : 59-63. PMID: 1753253 4. Chopin, P. and Briley, M. 1992. Psychopharmacology. 106: 26-30. PMID: 1738791 5. Radicheva, N., et al. 1996. Methods Find Exp Clin Pharmacol. 18: 301-308. PMID: 8817464 6. Ago, Y., et al. 2011. J. Pharmacol. Sci. 116: 6-17. PMID: 21498956
Soluble in ethanol (4 mg/ml), DMSO (10 mg/ml), water (1:0.5), and chloroform (1:5).
Store at -20° C
256° C (lit.)
Acetylcholinesterase: IC50 = 410 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Thank you for your question. The compound, sc-200179, can be shipped at room temperature as the melting point range is from 281-283ºC. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing firstname.lastname@example.org, or using the Live Chat function on our website.
Rated 5 out of
Galanthamine Hydrobromide was reported asGalanthamine Hydrobromide was reported as a acetylcholinesterase inhibitor, usually used in alzheimer research. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.