Galacto-N-biose (CAS 20972-29-6)
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Galacto-N-biose represents a disaccharide composed of two monosaccharides: beta-D-galactose and N-acetyl-D-galactosamine. The scientific applications of Galacto-N-biose are diverse and manifold. It serves as useful for investigating the structure and functionality of glycoproteins, glycolipids, and proteoglycans. It facilitates the exploration of carbohydrates′ contributions to cell-cell and cell-matrix interactions, as well as immune responses. Some employ it to study the mechanisms of enzymes engaged in glycosylation reactions. The mechanism of action of Galacto-N-biose relies on its distinct structure. The glycosidic bond connecting the two monosaccharides, beta-D-galactose and N-acetyl-D-galactosamine, is integral to its function. This bond is established when the hydroxyl group of the galactose molecule attaches to the nitrogen atom of the galactosamine molecule. The stability of this bond is further reinforced by hydrogen bonding between the two molecules.
Galacto-N-biose (CAS 20972-29-6) References
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- Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I. | Suzuki, R., et al. 2008. J Biol Chem. 283: 13165-73. PMID: 18332142
- Identification of lacto-N-Biose I phosphorylase from Vibrio vulnificus CMCP6. | Nakajima, M. and Kitaoka, M. 2008. Appl Environ Microbiol. 74: 6333-7. PMID: 18723650
- One-pot enzymatic production of beta-D-galactopyranosyl-(1-->3)-2-acetamido-2-deoxy-D-galactose (galacto-N-biose) from sucrose and 2-acetamido-2-deoxy-D-galactose (N-acetylgalactosamine). | Nishimoto, M. and Kitaoka, M. 2009. Carbohydr Res. 344: 2573-6. PMID: 19850285
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- Novel substrate specificities of two lacto-N-biosidases towards β-linked galacto-N-biose-containing oligosaccharides of globo H, Gb5, and GA1. | Gotoh, A., et al. 2015. Carbohydr Res. 408: 18-24. PMID: 25839135
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- Galacto-N-biose is neuroprotective against glutamate-induced excitotoxicity in vitro. | Shinoda, Y., et al. 2016. Eur J Pharmacol. 791: 711-717. PMID: 27729249
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Galacto-N-biose, 1 mg | sc-257553 | 1 mg | $182.00 | |||
Galacto-N-biose, 2 mg | sc-257553A | 2 mg | $338.00 | |||
Galacto-N-biose, 5 mg | sc-257553B | 5 mg | $1030.00 | |||
Galacto-N-biose, 10 mg | sc-257553C | 10 mg | $1238.00 | |||
Galacto-N-biose, 25 mg | sc-257553D | 25 mg | $2606.00 |