Anti-GABP-β1/2 Antibody (E-1) is a mouse monoclonal IgG1 κ GABP-β1/2 antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 131-395 mapping at the C-terminus of GABP-β1 of human origin
Anti-GABP- beta 1/2 Antibody (E-1) is recommended for detection of GABP-β1 and GABP-β2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and porcine
Anti-GABP- beta 1/2 Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-271531 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of GABP-β1/2 (E-1): sc-271531.
m-IgG Fc BP-HRP is the preferred secondary detection reagent for GABP-β1/2 Antibody (E-1) for WB applications. This reagent is now offered in a bundle with GABP-β1/2 Antibody (E-1) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
GABP-β1/2 Antibody (E-1) is a high quality monoclonal GABP- beta 1/2 antibody (also designated GABP-β1/2 antibody) suitable for the detection of the GABP- beta 1/2 protein of mouse, rat and human origin. GABP-β1/2 Antibody (E-1) is available as both the non-conjugated anti-GABP- beta 1/2 antibody form, as well as multiple conjugated forms of anti-GABP- beta 1/2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-α and a GABP-α-associated subunit, GABPβ. GABPα binds to a specific DNA sequence and GABPβ exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABPβ is expressed in both the cytoplasm and the nucleus, whereas GABPα is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABPαβ heterodimer or a GABPαb heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABPαβ tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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