GABP-α Antibody (H-2) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
raised against amino acids 1-180 of GABP-α of human origin
recommended for detection of GABP-α of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
TransCruz reagent for Gel Supershift and ChIP applications (sc-28311 X, 200 µg/0.1 ml)
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GABP-α Antibody (H-2) for WB and IHC(P) applications. These reagents are now offered in bundles with GABP-α Antibody (H-2) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-α and a GABP-α-associated subunit, GABP-β. GABP-α binds to a specific DNA sequence and GABP-β exists as β1 and β2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP-β is expressed in both the cytoplasm and the nucleus, whereas GABP-α is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABPαβ heterodimer or a GABPαb heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABPαβ tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.