Folotyn CAS: 146464-95-1
MF: C23H23N7O5
MW: 477.47
An inhibitor of DHFR (dihydrofolate reductase).

Folotyn (CAS 146464-95-1)

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Alternate Names: 10-propargyl-10-deazaaminopterin; Pralatrexate
Application: Folotyn is an inhibitor of DHFR (dihydrofolate reductase)
CAS Number: 146464-95-1
Purity: ≥98%
Molecular Weight: 477.47
Molecular Formula: C23H23N7O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Folotyn acts an inhibitor of DHFR (dihydrofolate reductase)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (28 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). Insoluble in chloroform.
Storage :
Store at room temperature
Melting Point :
349.84° C (Predicted)
Boiling Point :
804.07° C (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.70 (Predicted)
pK Values :
pKa: 3.53 (Predicted), pKb: 5.66 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00920897
SMILES :
C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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