Anti-folliculin Antibody (D-4) is a mouse monoclonal IgG1 κ folliculin antibody, cited in 2 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 555-579 at the C-terminus of folliculin of human origin
folliculin Antibody (D-4) is recommended for detection of folliculin of human origin by WB, IP, IF and ELISA
Anti-folliculin Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of folliculin (D-4): sc-271558.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for folliculin Antibody (D-4) for WB applications. These reagents are now offered in bundles with folliculin Antibody (D-4) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
folliculin Antibody (D-4) is a high quality monoclonal folliculin antibody (also designated folliculin antibody) suitable for the detection of the folliculin protein of human origin. folliculin Antibody (D-4) is available as both the non-conjugated anti-folliculin antibody form, as well as multiple conjugated forms of anti-folliculin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Birt-Hogg-Dubε (BHD) syndrome is a rare autosomal dominant cancer syndrome characterized by kidney tumors, benign tumors of the hair follicle and spontaneous pneumothorax. BHD is also associated with neoplastic colonic polyps. The BHD gene maps to chromosome 17p11.2 and encodes the protein folliculin. Folliculin is widely expressed. Notably, folliculin is expressed in the kidney, lung and skin, where BHD tumors arise. Specifically, the (C)8 tract in exon 11 is a mutational hot spot in BHD. BHD appears to have reduced penetrance or late onset. In a study of the renal tumors in 30 BHD patients, preoperative computed tomography scans detect a mean of 5.3 tumors per patient with a range 1-28 tumors. Multiple and bilateral tumors appear at a mean of 50.7 years.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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