(+)-Fluprostenol is the optically active enantiomer of fluprostenol (sc-201336). It is a metabolically stable analog of PGF2α and a potent FP prostanoid receptor (PGF2αR) agonist. The expected potency of (+)-fluprostenol is twice that of (+/-)-fluprostenol for PGF2α binding to human and rat FP receptors. (+)-Fluprostenol is an effective inhibitor of rat adipose precursor differentiation in primary cultures.
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