Flumethasone pivalateThe pivalic acid ester of Elumethasone

Flumethasone pivalate (CAS 2002-29-1)

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Synonym: 6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate)
Application: The pivalic acid ester of Elumethasone
CAS Number: 2002-29-1
Molecular Weight: 494.57
Molecular Formula: C27H36F2O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Flumethasone pivalate is a topical difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. Flumethasone pivalate is a glucocorticoid receptor agonist used in studies on plasma transcortin binding. It binds to the nucleus causing a variety of genetic activations and repressions. The anti-inflammatory action of flumethasone is thought to involve lipocortins and phospholipase A2 inhibitory proteins, which results in the inhibition of arachidonic acid and the control of prostaglandin and leukotriene biosynthesis.

Physical State :
Solid
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
TU3832010
PubChem CID :
443980
SMILES :
CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C)F

Download SDS (MSDS)

Certificate of Analysis

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