FGIN-1-43 CAS: 145040-29-5
MF: C28H36Cl2N2O
MW: 487.51
A specific ligand for mitochondrial diazepam binding inhibitor receptor.

FGIN-1-43 (CAS 145040-29-5)

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Alternate Names: N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide
Application: FGIN-1-43 is a specific ligand for mitochondrial diazepam binding inhibitor receptor
CAS Number: 145040-29-5
Molecular Weight: 487.51
Molecular Formula: C28H36Cl2N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data (including water content).
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FGIN-1-43 is a potent and specific ligand for mitochondrial diazepam binding inhibitor receptor.


References

1. Romeo, E., et al. 1992. J. Pharmacol. Exp. Ther. 262: 971-978.
2. Kozikowski, A.P., et al. 1993. J. Med. Chem. 36: 2908-2920.

Physical State :
Solid
Solubility :
Soluble in DMSO (50 mM).
Storage :
Store at room temperature
Melting Point :
270.09° C (Predicted)
Boiling Point :
648.53° C at 760 mmHg (Predicted)
Density :
1.14 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
IC50 :
Alpha-1d adrenergic receptor: IC50 >1 µM (rat); GABA-A receptor; anion channel: IC50 >1 µM (rat); Glutamate receptor ionotropic, AMPA 1: IC50 >1 µM (mouse); Dopamine D3 receptor: IC50 >1 µM (rat)
Ki Data :
Peripheral-type benzodiazepine receptor: Ki= 3.6 nM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
PubChem CID :
MDL Number :
MFCD00917208
SMILES :
CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=C1C=C(C=C2)Cl)C3=CC=C(C=C3)Cl

Download SDS (MSDS)

Certificate of Analysis

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