EtretinatePsoriasis medication shown to cause birth defects

Etretinate (CAS 54350-48-0)

Etretinate | CAS 54350-48-0 is rated 5.0 out of 5 by 1.
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Synonym: Tegison
Application: Psoriasis medication shown to cause birth defects
CAS Number: 54350-48-0
Purity: ≥98%
Molecular Weight: 354.48
Molecular Formula: C23H30O3
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Etretinate is an aromatic retinoid.


References

1. Brazzell, R.K. and Colburn, W.A. 1982. J Am Acad Dermatol. 6: 643–651. 2. Helander, I. and Hopsu-Havu, V.K. 1986. Clin Exp Dermatol. 11: 574-577 (

Physical State :
Solid
Solubility :
Soluble in water (partly), alcohol, chloroform, and ethyl acetate.
Storage :
Store at -20° C
Melting Point :
104-105°C (lit.)
Boiling Point :
~506.4° C at 760 mmHg (Predicted)
Density :
~1.0 g/cm3 (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
RA6620000
PubChem CID :
5282375
MDL Number :
MFCD00866624
EC Number :
259-119-3
Beilstein Registry :
2225606
SMILES :
CCOC(=O)\\C=C(C)\\C=C\\C=C(C)\\C=C\\C1=C(C)C(C)=C(OC)C=C1C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Shima et al Shima et al. (PubMed ID 25408646) treated localized scleroderma with the vitamin A derivative, etretinate. Eretinate was shown to reduce collagen synthesis. -SCBT Publication Review
Date published: 2015-06-12
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