(+)-Etomoxir sodium saltA PPARα agonist and an irreversible CPT-1 inhibitor

(+)-Etomoxir sodium salt (CAS 828934-41-4)

(+)-Etomoxir sodium salt | CAS 828934-41-4 is rated 5.0 out of 5 by 2.
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Synonym: R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt
Application: A PPARα agonist and an irreversible CPT-1 inhibitor
CAS Number: 828934-41-4
Purity: ≥98%
Molecular Weight: 320.74
Molecular Formula: C15H18ClO4•Na
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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(+)-Etomoxir sodium salt is a PPARα activator; and an irreversible O-carnitine palmitoyltransferase-1 (CPT-1) inhibitor. (+)-Etomoxir sodium salt hydrate also inhibits β-oxidation in mitochondria.


References

Ku, F. Y., et al. Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J. Lipid Res. 44, 415-423, (2003)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
57345784
MDL Number :
MFCD11044452
SMILES :
C1[C@](O1)(CCCCCCOC2=CC=C(C=C2)Cl)C(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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(+)-Etomoxir sodium salt  Product Citations

See how others have used (+)-Etomoxir sodium salt. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27364555  Cheng, CT. et al. 2016. Cancer Res. 76: 5006-18.

Citations 1 to 1 of 1 total

What is the shipping temperature of this product?

Asked by: hawkeye11
Thank you for your question. The compound, sc-215009, is shipped at ambient temperatures. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-02-07
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Rated 5 out of 5 by from The inhibitor works well The inhibitor works well. It can inhibit the target molecule effectively.I will continue purchase your other inhibitor for further use.
Date published: 2015-10-15
Rated 5 out of 5 by from Li J; et al Li J; et al. (PubMed ID: 26226833) determined that (+)-Etomoxir sodium salt, an inhibitor of CPT1, significantly inhibited the decrease of bone mineral density in high fat fed mice. -SCBT Publication Review
Date published: 2015-02-25
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