Ethyl 3,4-dihydroxybenzylidenecyanoacetate is an inhibitor of 12-LO (12-lipoxygenase) and 15-LO (15-lipoxygenase). 12-LO is an enzyme involved in the lipoxygenase pathway and plays a major role in promoting prostate cancer progression and metastasis. 15-LO enzyme has been associated with antherosclerosis and cancer.
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See how others have used Ethyl 3,4-dihydroxybenzylidenecyanoacetate. Click on the entry to view the PubMed entry .
PMID: # 27709605 Rodríguez, M.|Márquez, S.|de la Rosa, JV.|Alonso, S.|Castrillo, A.|Sánchez Crespo, M.|Fernández, N.| et al. 2017. Immunology. 150: 184-198.
PMID: # 26673542 Rodríguez, M. et al. 2016. Biochem. Pharmacol. 102: 78-96.
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