Estrogen Receptor alpha Antibody (2Q418) is a mouse monoclonal IgG2a κ, cited in 34 publications, provided at 200 µg/ml
raised against amino acids 495-595 of Estrogen Receptor alpha of bovine origin
recommended for detection of Estrogen Receptor alpha of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including bovine
m-IgGκ BP-HRP is the preferred secondary detection reagent for Estrogen Receptor alpha Antibody (2Q418) for WB and IHC(P) applications. This reagent is now offered in a bundle with Estrogen Receptor alpha Antibody (2Q418) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.