Anti-ErbB4/HER4 Antibody (C-7) is a mouse monoclonal IgG2a κ ErbB4/HER4 antibody, cited in 47 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 1291-1308 at the C-terminus of ErbB-4 of human origin
ErbB4/HER4 Antibody (C-7) is recommended for detection of ErbB-4 of mouse, rat, human and origin by WB, IP, IF, IHC(P), FCM and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
Anti-ErbB4/HER4 Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ErbB4/HER4 (C-7): sc-8050.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ErbB4/HER4 Antibody (C-7) for WB and IHC(P) applications. These reagents are now offered in bundles with ErbB4/HER4 Antibody (C-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ErbB-4 Antibody (C-7) is a high quality monoclonal ErbB-4 antibody (also designated ERBB4 antibody, erb-b2 receptor tyrosine kinase 4 antibody, or HER4 antibody) suitable for the detection of the ErbB-4 protein of mouse, rat and human origin. ErbB-4 Antibody (C-7) is available as both the non-conjugated anti-ErbB-4 antibody form, as well as multiple conjugated forms of anti-ErbB-4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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