Epigenetic Multiple LigandA cell-permeable bis-arylidene compound

Epigenetic Multiple Ligand (CAS 1020399-52-3)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 68ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: PRMT Inhibitor IV
Application: A cell-permeable bis-arylidene compound
CAS Number: 1020399-52-3
Molecular Weight: 623.9
Molecular Formula: C19H12Br4O4
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Epigenetic Multiple Ligand is a cell-permeable bis-arylidene compound that acts as an epi-ML and inhibits substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1, with weak effect on the process of Np13p by PRMT1. Epigenetic Multiple Ligand has been shown to induce either apoptosis or granulocytic differentiation among U937 cell population. It is an inhibitor of PRMT.


1. Mai, Antonello., et al., 2008. epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. Journal of medicinal chemistry. 51(7): 2279-90. PMID: 18348515

Physical State :
Solubility :
Soluble in DMSO (100 mg/ml).
Storage :
Store at 4° C
Boiling Point :
615.56° C at 760 mmHg (Predicted)
Density :
2.14 g/cm3 (Predicted)
Refractive Index :
n20D 1.77 (Predicted)
IC50 :
RmtA: IC50 = 29 µM (Emericella nidulans)
pK Values :
pKa: 5.94 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 71ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 3ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.