ent-AbacavirAn enatiomer of the nucleoside reverse transcriptase inhibitor (NRTI) Abacavir

ent-Abacavir (CAS 136470-79-6)

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Synonym: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methano
Application: An enatiomer of the nucleoside reverse transcriptase inhibitor (NRTI) Abacavir
CAS Number: 136470-79-6
Molecular Weight: 286.33
Molecular Formula: C14H18N6O
* Refer to Certificate of Analysis for lot specific data (including water content).
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ent-Abacavir is the enatiomer of the nucleoside reverse transcriptase inhibitor (NRTI) Abacavir [also called Ziagen (sc-338739)] with similar antiviral properties. NRTIs work by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme.


References

1. Hanumegowda, U.M. et al. 2010. Chem. Res. Toxicol. 23(4): 749-755. PMID: 20356072

2. Prasse, C. et al. 2010. Environ. Sci. Technol. 44(5): 1728-1735. PMID: 20108960

3. Krejcová, R. et al. 2000. Biochem. Pharmacol. 60(12): 1907-1913. PMID: 11108807

4. Holy, A. 2003. Curr. Pharm. Des. 9(31): 2567-2592. PMID: 14529543

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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