Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ENSA Antibody (L7Q) is a high quality monoclonal ENSA antibody (also designated ENSA antibody) suitable for the detection of the ENSA protein of mouse, rat and human origin. ENSA Antibody (L7Q) is available as the non-conjugated anti-ENSA antibody. ATP-dependent potassium K(ATP) channels regulate the polarity of the cell membrane, which affects cell metabolism and insulin secretion. When ATP levels rise in response to an increased rate of glucose metabolism, the K(ATP) channels close, which stimulates the cells to secrete Insulin. K(ATP) channels are composed of two structurally unrelated subunits; a Kir6.0 subfamily component and a sulfonylurea receptor (SUR) component. ENSA (alpha-endosulfine), also known as ARPP-19e, is a 121 amino acid endogenous ligand for SUR. ENSA inhibits the binding of sulfonylurea to the SUR component of the K(ATP) channel, thereby reducing channel activity and stimulating the secretion of Insulin. ENSA is localized to the cytoplasm and widely expressed in tissues, with high expression in brain and muscle and low expression in pancreas. ENSA is phosphorylated by PKA and exists as 2 isoforms, designated alpha and beta, produced by alternative splicing.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.