EGTA/AMA membrane-permeable form of the EGTA Ca2+-chelating agent

EGTA/AM (CAS 99590-86-0)

EGTA/AM | CAS 99590-86-0 is rated 5.0 out of 5 by 1.
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Synonym: Ethyleneglycol-bis(β-aminoethyl)-N,N,N′,N′-tetraacetoxymethyl Ester
Application: A membrane-permeable form of the EGTA Ca2+-chelating agent
CAS Number: 99590-86-0
Purity: ≥95%
Molecular Weight: 668.6
Molecular Formula: C26H40N2O18
* Refer to Certificate of Analysis for lot specific data (including water content).
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EGTA/AM is a membrane-permeable form of the EGTA Ca2+-chelating agent.


References

Garcia, J.G., et al. 1992. Blood 79, 2056. Kuriyama, S., et al. 1992. Brain Res. 579, 227. Maki, A., et al. 1992. FASEB J. 6, 919. Negre-Salvayre, A., and Salvayre, R. 1992. Biochim. Biophys. Acta 1123, 207. Ichinose, M., et al. 1992. Biochem. Biophys. Res. Commun. 182, 372. Hong, M., and Moody, T.W. 1991. Peptides 12, 1315. Schnellmann, R.G. 1991. J. Biochem. Toxicol. 6, 299.

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in DMF, and DMSO (20 mg/ml).
Storage :
Store at -20° C
Boiling Point :
664.19° C at 760 mmHg (Predicted)
Density :
1.30 g/mL (Predicted)
Refractive Index :
n20D 1.49 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
121907
MDL Number :
MFCD00077339
SMILES :
CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

Download SDS (MSDS)

Certificate of Analysis

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EGTA/AM  Product Citations

See how others have used EGTA/AM. Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

PMID: # 31204282  Li, M.|Zhang, CS.|Zong, Y.|Feng, JW.|Ma, T.|Hu, M.|Lin, Z.|Li, X.|Xie, C.|Wu, Y.|Jiang, D.|Li, Y.|Zhang, C.|Tian, X.|Wang, W.|Yang, Y.|Chen, J.|Cui, J.|Wu, YQ.|Chen, X.|Liu, QF.|Wu, J.|Lin, SY.|Ye, Z.|Liu, Y.|Piao, HL.|Yu, L.|Zhou, Z.|Xie, XS.|Hardie, DG.|Lin, SC.| et al. 2019. Cell Metab.

PMID: # 29849062  Kyrmizi, I. et al. 2018. Nat Microbiol. 3: 791-803.

PMID: # 25720963  Medina, DL. et al. 2015. Nature cell biology. 17: 288-99.

PMID: # 22036572  Yao, J. et al. 2011. Cell. 147: 666-77.

Citations 1 to 4 of 4 total
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Rated 5 out of 5 by from Various publications cite the use of EGTA/AM Various publications cite the use of EGTA/AM as a Ca2+ chelating agent. -SCBT Publication Review
Date published: 2015-04-07
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