Ecotin, E. coli CAS: 87928-05-0
MW: 32200
A strong broad range inhibitor of serine proteases. Also binds trypsin.

Ecotin, E. coli (CAS 87928-05-0)

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Application: Ecotin, E. coli is a strong broad range inhibitor of serine proteases. Also binds trypsin
CAS Number: 87928-05-0
Molecular Weight: 32200
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ecotin, E. coli is a strong broad range inhibitor of prothrombin (serine proteases). The compound exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor X(Factor Xa), Factor XII(Factor XIIa), kallikrein, and trypsin. Ecotin, E. coli also acts as an effective inhibitor of MMP(collagenase), and exhibits biological activity by binding trypsin in the picomolar range. Ecotin, E. coli is an inhibitor of granzyme B.


References

McGrath, M.E., et al. 1995. Protein Sci. 4, 141. Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915. McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.

Physical State :
Liquid
Storage :
Store at -80° C
IC50 :
serine proteases: IC50 = 1 pM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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