Ebselen Oxide is used for the treatment of cerebral infarctions and is an excellent scavenger of peroxynitrite. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, which indicats that it can serve as a negative control for Ebselen. Ebselen Oxide is an inhibitor of P504S.
1 Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys Acta 1303 111-118 (1996).
Soluble in PBS (pH 7.2) (~0.15 mg/mL), ethanol (10 mg/mL), DMSO (10 mg/mL), and DMF (10 mg/mL).
Store at -20° C
156.71° C (Predicted)(Mean or Weighted MP)
277.25° C at 760 mmHg (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Tan et alTan et al. (PubMed ID 25912997) found that Ebselen Oxide protected retinal M ller cells and their microvasculature against hypoxia-induced injury by reducing oxidative stress, vascular damaging factors and inflammation. -SCBT Publication Review
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