Ebselen OxideCAS: 104473-83-8
MF: C13H9NO2Se
MW: 290.2
An excellent scavenger of peroxynitrite.

Ebselen Oxide (CAS 104473-83-8)

Ebselen Oxide | CAS 104473-83-8 is rated 5.0 out of 5 by 1.
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Synonym: NSC 639772; 1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
Application: An excellent scavenger of peroxynitrite
CAS Number: 104473-83-8
Purity: ≥98%
Molecular Weight: 290.2
Molecular Formula: C13H9NO2Se
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Ebselen Oxide is used for the treatment of cerebral infarctions and is an excellent scavenger of peroxynitrite. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, which indicats that it can serve as a negative control for Ebselen. Ebselen Oxide is an inhibitor of P504S.


References

1 Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys Acta 1303 111-118 (1996).

Physical State :
Solid
Solubility :
Soluble in PBS (pH 7.2) (~0.15 mg/mL), ethanol (10 mg/mL), DMSO (10 mg/mL), and DMF (10 mg/mL).
Storage :
Store at -20° C
Melting Point :
156.71° C (Predicted)(Mean or Weighted MP)
Boiling Point :
277.25° C at 760 mmHg (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
368655
MDL Number :
MFCD18427988
SMILES :
C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2=O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Tan et al Tan et al. (PubMed ID 25912997) found that Ebselen Oxide protected retinal M ller cells and their microvasculature against hypoxia-induced injury by reducing oxidative stress, vascular damaging factors and inflammation. -SCBT Publication Review
Date published: 2015-03-08
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