DSP-4 hydrochloride CAS: 40616-75-9
MF: C11H15BrClN•HCl
MW: 313.06
An adrenergic neuron blocking agent with inhibitory effects on the uptake of noradrenaline.

DSP-4 hydrochloride (CAS 40616-75-9)

DSP-4 hydrochloride | CAS 40616-75-9 is rated 5.0 out of 5 by 1.
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Alternate Names: N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride
Application: DSP-4 hydrochloride is An adrenergic neuron blocking agent with inhibitory effects on the uptake of noradrenaline
CAS Number: 40616-75-9
Purity: ≥95%
Molecular Weight: 313.06
Molecular Formula: C11H15BrClN•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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DSP-4 hydrochloride is an adrenergic neuron blocking agent with long-lasting inhibitory effect on the uptake of noradrenaline (norepinephrine) in brain slices in vitro.


References

1. Ross, S.B., et al. 1973. Acta Pharm. Suec. 10: 29-42. PMID: 4145284
2. Jonsson, G., et al. 1981. Eur. J. Pharmacol. 72: 173-188. PMID: 6265244
3. Fontani, G., et al. 1984. Behav. Neural Biol. 40: 213-326. PMID: 6233963

Physical State :
Solid
Solubility :
Soluble in water (48 mg/ml), ethanol (49.00 - 51.00 mg/ml), and 0.1 M NaOH (7 mg/ml).
Storage :
Store at room temperature
Refractive Index :
n20D 1.55 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
DP1726100
PubChem CID :
MDL Number :
MFCD00043241
Beilstein Registry :
4020910
SMILES :
CCN(CCCl)CC1=CC=CC=C1Br.Cl

Download SDS (MSDS)

Certificate of Analysis

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DSP-4 hydrochloride (CAS 40616-75-9)  Product Citations

See how others have used DSP-4 hydrochloride (CAS 40616-75-9). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 32298434  Invest. Ophthalmol. Vis. Sci. 61: 17.

PMID: # 32376471  Exp. Eye Res. 195: 108048.

PMID: # 32299228  Exp. Biol. Med. (Maywood). 1535370220919361.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from Scullion Scullion, GA. et al. (PubMed 19720115) reported that the central noradrenergic depletion by DSP-4 prevents stress-induced memory impairments in the object recognition task. -SCBT Publication Review
Date published: 2015-03-01
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