Anti-DREAM Antibody (A-9) is a mouse monoclonal IgG2b κ DREAM antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 1-214 representing full length DREAM of human origin
Anti-DREAM Antibody (A-9) is recommended for detection of DREAM of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-DREAM Antibody (A-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DREAM (A-9): sc-166916.
m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for DREAM Antibody (A-9) for WB applications. These reagents are now offered in bundles with DREAM Antibody (A-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DREAM Antibody (A-9) is a high quality monoclonal DREAM antibody (also designated DREAM antibody) suitable for the detection of the DREAM protein of mouse, rat and human origin. DREAM Antibody (A-9) is available as both the non-conjugated anti-DREAM antibody form, as well as multiple conjugated forms of anti-DREAM antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DREAM (for DRE-antagonist modulator) is a Ca2+-regulated transcriptional repressor that specifically binds to the downstream regulatory elements (DRE). DRE is a regulatory sequence that silences basal transcription and is localized to the promoter region of the gene encoding human prodynorphin, an opioid peptide involved in memory acquisition and pain. DREAM forms functional homotetramers that are required for the interaction with the DRE. This association is highly influenced by calcium, as an increase in Ca2+ directly inhibits DREAM binding and thereby blocks the repressor activity of DREAM. DREAM transcripts are detected in brain, thymus and thyroid gland, and it is expressed as a nuclear protein. DREAM has been shown to inhibit transcription of other proteins containing DRE-like motifs, including the gene encoding for the AP-1 transcription factor c-Fos, suggesting that DREAM may influence a wide variety of cellular genes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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