Doxepin hydrochloride is a highly potent Histamine H1 Receptor (histamine H1) antagonist. Doxepin hydrochloride also binds to histamine H4 receptor. Doxepin hydrochloride is an inhibitor of AR and mAChR M.
1. Tran, V.T., et al. 1981. Eur. J. Pharmacol. 70: 501-509. PMID: 7238574 2. Luchins, D.J. 1983. Am J Psychiatry. 140: 1006-1009. PMID: 6346907 3. Nguyen, T., et al. 2001. Mol. Pharmacol. 59: 427-433. PMID: 11179435
Soluble in water (100 mM), chloroform (1:2), alcohol (1:1), methanol, and DMSO.
Store at room temperature
413.3° C at 760 mmHg (Predicted)
n20D ~1.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Certificate of Analysis
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Rated 5 out of
Park HJ; et alPark HJ; et al. (PubMed ID: 26253075) determined that Doxepin hydrochloride inhibited EAAT3 activity and glutamatergic neurotransmission. -SCBT Publication Review
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