Dovitinib Dilactic acid CAS: 852433-84-2
MF: C21H21FN6O.2C3H6O3
MW: 572.59
A growth factor receptor kinase inhibitor that targets Flt-3, c-KIT, PDGFR, and CSF.

Dovitinib Dilactic acid (CAS 852433-84-2)

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Application: Dovitinib Dilactic acid is a growth factor receptor kinase inhibitor that targets Flt-3, c-KIT, PDGFR, and CSF
CAS Number: 852433-84-2
Purity: ≥99%
Molecular Weight: 572.59
Molecular Formula: C21H21FN6O.2C3H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Dovitinib Dilactic acid is a potent, non-specific growth factor receptor kinase inhibitor with effects against FLT-3, c-KIT, VEGFR, PDGFRβ and CSF-1R, respectively.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (90 mg/ml at 25 °C), water (70 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), and saline (30 mg/ml at 25 °C).
Storage :
Store at -20° C
Refractive Index :
n20D ~1.69 (Predicted)
IC50 :
Flt3: IC50 = 1 nM; c-Kit: IC50 = 2 nM; FGFR1: IC50 = 8 nM; FGFR3: IC50 = 9 nM; VEGFR1: IC50 = 10 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD22420807
SMILES :
CC(C(=O)O)O.CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4\\C(=C5C(=NC4=O)C=CC=C5F)N)/N3

Download SDS (MSDS)

Certificate of Analysis

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Dovitinib Dilactic acid (CAS 852433-84-2)  Product Citations

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PMID: # 34438041  García-Quiroz, J.|Cárdenas-Ochoa, N.|García-Becerra, R.|Morales-Guadarrama, G.|Méndez-Pérez, EA.|Santos-Cuevas, C.|Ramírez-Nava, GJ.|Segovia-Mendoza, M.|Prado-García, H.|Avila, E.|Larrea, F.|Díaz, L.| et al. 2021. J Steroid Biochem Mol Biol. 214: 105979.

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