DMCM hydrochloride is a benzodiazepine inverse agonist. Exhibits strong convulsant and anxiogenic activity. DMCM hydrochloride is an inhibitor of GABA Receptor.
Petersen (1983) DMCM: a potent convusive benzodiazepine receptor ligand. Eur.J.Pharmacol. 94 117. Sieve et al (2001) Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacol. 153 180. Conto et al (2005) Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist. Pharmacol.Biochem.Behav. 82 417.
See how others have used DMCM hydrochloride (CAS 82499-00-1). Click on the entry to view the PubMed entry .
PMID: # 26577018 Kratsman, N.|Getselter, D.|Elliott, E.| et al. 2016. Neuropharmacology. 102: 136-45.
PMID: # 32328689 Anal Bioanal Chem. 4037-4043.