DirithromycinA semi-synthetic derivative of Erythromycin that acts as an antibacterial

Dirithromycin (CAS 62013-04-1)

Dirithromycin | CAS 62013-04-1 is rated 5.0 out of 5 by 1.
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Synonym: Dynabac
Application: A semi-synthetic derivative of Erythromycin that acts as an antibacterial
CAS Number: 62013-04-1
Molecular Weight: 835.07
Molecular Formula: C42H78N2O14
* Refer to Certificate of Analysis for lot specific data (including water content).
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Dirithromycin is a semi-synthetic derivative of Erythromycin, and an antibacterial. The compound is a more lipid soluble prodrug of 9S-erythromycyclamine.


References

Firl, J., et al.: J. Antibiot., 43, 1271 (1990), Counter, et al.: Antimicrob. Agents Chemother., 35, 1116 (1991), Castaldo, R., et al.: Clin. Ther., 25, 542 (2003),

Appearance :
Crystalline powder
Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6917067
SMILES :
CC[C@@H]1[C@@]([C@@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O

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Certificate of Analysis

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Rated 5 out of 5 by from Counter et al Counter et al. (PubMed ID 1929252) found that subcutaneous delivery of dirithromycin was more efficient than erythromycin against experimental infections in mice. -SCBT Publication Review
Date published: 2015-05-18
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