Dihydrocytochalasin BA cell morphology and motility and inducer

Dihydrocytochalasin B (CAS 39156-67-7)

Dihydrocytochalasin B | CAS 39156-67-7 is rated 5.0 out of 5 by 1.
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Application: A cell morphology and motility and inducer
CAS Number: 39156-67-7
Purity: >98%
Molecular Weight: 481.63
Molecular Formula: C29H39NO5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Dihydrocytochalasin B induces changes in cell morphology and motility with no effect on sugar transport. Dihydrocytochalasin B is used as specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Dihydrocytochalasin B also disrupts the equilibrium between monomeric and polymeric actin.


References

Lin, D.C., and Lin, S. 1978. J. Biol. Chem. 253, 1415.

Physical State :
Solid
Solubility :
Soluble in dimethylformamide (492 mg/ml), DMSO (371 mg/ml), ethanol (35 mg/ml), acetone (10 mg/ml), and methanol. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
203-205° C
Refractive Index :
n20D 1.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
RO0205000
PubChem CID :
6438347
Merck Index :
14: 2790
MDL Number :
MFCD12910542
EC Number :
254-324-4
SMILES :
CC1CCCC(CCC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Trendowski M; et al Trendowski M; et al. (PubMed ID: 25563824) determined that Dihydrocytochalasin B in combination with doxorubicin had significant cytotoxicity against ADR-resistant P388/ADR leukemia. -SCBT Publication Review
Date published: 2015-04-28
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