Dihydrocytochalasin B induces changes in cell morphology and motility with no effect on sugar transport. Dihydrocytochalasin B is used as specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Dihydrocytochalasin B also disrupts the equilibrium between monomeric and polymeric actin.
Lin, D.C., and Lin, S. 1978. J. Biol. Chem. 253, 1415.
Soluble in dimethylformamide (492 mg/ml), DMSO (371 mg/ml), ethanol (35 mg/ml), acetone (10 mg/ml), and methanol. Insoluble in water.
Store at -20° C
n20D 1.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Trendowski M; et alTrendowski M; et al. (PubMed ID: 25563824) determined that Dihydrocytochalasin B in combination with doxorubicin had significant cytotoxicity against ADR-resistant P388/ADR leukemia. -SCBT Publication Review
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