Dihydro ArtemisininAn active antimalarial metabolite

Dihydro Artemisinin (CAS 71939-50-9)

Dihydro Artemisinin | CAS 71939-50-9 is rated 5.0 out of 5 by 1.
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Synonym: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol;β-Dihydroartemisinin; Alaxin; Cotecxin; Cotexin; DHQHS 2; Dihydroartemisinine; Dihydroqinghaosu; USP Artemether Related Compound A
Application: An active antimalarial metabolite
CAS Number: 71939-50-9
Purity: ≥99%
Molecular Weight: 284.35
Molecular Formula: C15H24O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Dihydro Artemisinin is an active antimalarial metabolite. Dihydro Artemisinin is also the main metabolite of Artemisinin, Arteether, Artemether, Artesunate.


References

de Vries, P., et al.: Drugs, 52, 818 (1996), Kamolrat, S., et al.: Antimicrob. Agents Chemother., 47, 3795 (2003), Mithwani, S., et al.: Br. J. Clin. Pharmacol., 57, 146 (2004),

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (57 mg/ml) at 25° C, ethanol (14 mg/ml) at 25° C, and water (<1 mg/ml) at 25° C.
Storage :
Store at -20° C
Melting Point :
164-165° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
46781295
SMILES :
CC1CC[C@H]2[C@@H](C)C(O)O[C@@H]3O[C@]4(C)CCC1C23OO4

Download SDS (MSDS)

Certificate of Analysis

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Dihydro Artemisinin  Product Citations

See how others have used Dihydro Artemisinin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25371719  Guo, L. et al. 2014. Experimental and therapeutic medicine. 8: 1707-1712.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Cao Q; et al Cao Q; et al. (PubMed ID: 25575733)determined Dihydro Artemisinin inhibited the growth and inflammation (induced by TNF-a) of vascular smooth muscle cells, via ROS-mediated NF- B signal pathway. -SCBT Publication Review
Date published: 2015-05-25
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