DICAAn inhibitor of caspase-3 and caspase-7

DICA (CAS 613665-26-2)

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Application: An inhibitor of caspase-3 and caspase-7
CAS Number: 613665-26-2
Purity: 98%
Molecular Weight: 280.2
Molecular Formula: C10H11Cl2NO2S
* Refer to Certificate of Analysis for lot specific data (including water content).
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DICA is an inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site. Caspases are proteins that are critical to regulating the apoptotic pathway. These proteins cleave enzymes and proteins that are necessary for cell survival, in turn inducing apoptosis.


References

1. Hardy, J.A. 2004. Proc. Natl. Acad. Sci. U.S.A. 101: 12461-12466. PMID: 15314233

Physical State :
Solid
Solubility :
Soluble in methanol, and DMSO.
Storage :
Store at -20° C
Melting Point :
167.31° C
Boiling Point :
480.17° C at 760 mmHg (Predicted)
Density :
1.36 g/cm3 (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
448572
SMILES :
C1=CC(=C(C=C1Cl)Cl)OCC(=O)NCCS

Download SDS (MSDS)

Certificate of Analysis

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