DFB is a selective allosteric potentiator of metabotropic glutamate receptor type 5 (mGluR-5). DFB shows no agonist activity itself, but potentiates the action of other agonists at the mGluR-5 receptor site (3-6-fold), without any effect at other mGluR types.
1. O'Brien, J.A., et al. 2003. Mol. Pharmacol. 64: 731-740. PMID: 12920211
2. Zhang, Y., et al. 2005. J. Pharmacol. Exp. Ther. 315: 1212-1219. PMID: 16135701
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.