Dexamethasone Sodium PhosphateAn inducer of apoptosis and inhibitor of the sodium phosphate symporter

Dexamethasone Sodium Phosphate (CAS 2392-39-4)

Dexamethasone Sodium Phosphate | CAS 2392-39-4 is rated 5.0 out of 5 by 1.
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Synonym: (11b, 16a)-9-Fluoro-11,17,21-trihydroxy-16- methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt; Dexamethasone 21-Phosphate Disodium Salt; Ak-Dex; Baldex; Dalalone; Dezone; Hexadrol; Oradexon; Soldesam
Application: An inducer of apoptosis and inhibitor of the sodium phosphate symporter
CAS Number: 2392-39-4
Purity: ≥98%
Molecular Weight: 516.4
Molecular Formula: C22H28FO8P•2Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Dexamethasone Sodium Phosphate is a systemic corticosteroid. Dexamethasone Sodium Phosphate induces apoptosis and inhibits sodium phosphate symporter. Dexamethasone Sodium Phosphate is also used in the treatment of emetic effects of cancer therapy and epicondylitis. Dexamethasone Sodium Phosphate is an activator of GR.


References

Hayreh SS, Zimmerman B. Ophthalmology.110:1204-15 (2003). Li GF, Chen JH, Yang J et al. Di Yi Jun Yi Da Xue Xue Bao. 24:11-4 (2004). Chen Y, Chen XY. Ai Zheng. 21:498-503 (2002). Cassileth PA, Lusk EJ, Torri S et al. Arch Intern Med.143:1347-9 (1983).

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml).
Storage :
Store at 4° C
Melting Point :
233-240° C
Refractive Index :
n20D ~1.59 (Predicted)
Optical Activity :
α20/D +74°, c = 1 in water, dry basis
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
TU4056000
PubChem CID :
517289
Merck Index :
14: 2943
MDL Number :
MFCD00079105
EC Number :
219-243-0
Beilstein Registry :
6473066
SMILES :
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

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Certificate of Analysis

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Dexamethasone Sodium Phosphate  Product Citations

See how others have used Dexamethasone Sodium Phosphate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25318023  Shao, N. et al. 2014. Soft Matter. 10: 9153-8.

Citations 1 to 1 of 1 total

how is the uv spectra?

Asked by: sey62
Thank you for your question. It is unclear exactly what information you are requesting about this chemical, L-2-Amino-3-hydroxybutanoic acid 3-phosphate: sc-295240. Please contact our Technical Service Department and we would be happy to help you. Please call our European Support office toll-free at 00800 4573 8000, email europe@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2017-05-10

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical is supplied as a white to yellowish powder. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2017-01-16
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Rated 5 out of 5 by from Wang XW; et al Wang XW; et al. (PubMed ID: 26214469) confirmed that Dexamethasone Sodium Phosphate increased inhibition of proliferation in CEM cells and cytotoxic activity in Jurkat cells. -SCBT Publication Review
Date published: 2015-06-15
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