δ12-PGJ2 (δ12-Prostaglandin J2) is a decomposition product of PGD2 (sc-201221) that has shown potent antiviral and anit-proliferative activity. This compound has also been shown to induce apoptosis, and to inhibit phosphoinositide turnover. Conjugation with glutathione (sc-29094) is thought to enhance the cytotoxicity of δ12-PGJ2. Similar to other prostaglandins, it is often difficult to distinguish between biological activities derived directly from 'parent' molecules and those derived from metabolites thereof.
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