Decanoyl-p-nitroanilideA colorimetric substrate for FAAH.

Decanoyl-p-nitroanilide (CAS 72298-63-6)

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Application: A colorimetric substrate for FAAH.
CAS Number: 72298-63-6
Purity: 98%
Molecular Weight: 292.4
Molecular Formula: C16H24N2O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Decanoyl-p-nitroanilide is a synthetic fatty acid amide utilized as a probe for activity of FAAH (fatty acid amide hydrolase), the enzyme primarily responsible for degradation of the endocannabinoid Anandamide (sc-200790). FAAH accepts Decanoyl-p-nitroanilide as a substrate and upon amide hydrolysis releases an equivalent of p-nitroaniline which can be assayed at 382 nm (ε = 13500 M-1cm-1) with a UV-Vis spectrophotometer.


References

1. Patricelli, M.P., et al. 2001. Biochemistry. 40: 6107-6115. PMID: 11352748

Physical State :
Solid
Solubility :
Soluble in DMSO (25 mg/ml), ethanol (25 mg/ml), DMF (~20 mg/ml), 1:2 DMFO:PBS (pH 7.2) (0.6 mg/ml), and water (0.6 mg/ml) at 25° C.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
4124417
MDL Number :
MFCD00033992
SMILES :
CCCCCCCCCC(=O)NC1=CC=C(C=C1)[N+](=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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