DEAAn endocannabinoid agonist of the CB1 receptor

DEA (CAS 150314-35-5)

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Synonym: Docosatetraenylethanolamide
Application: An endocannabinoid agonist of the CB1 receptor
CAS Number: 150314-35-5
Molecular Weight: 375.59
Molecular Formula: C24H41NO2
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DEA is a potent endocannabinoid (anandamide analog) that activates CB1 receptors in microglia and binds to synaptosomal membranes (Ki = 34.4 nM). DEA is also cannabimimetic.


References

1. Hanus, L., et al. 1993. J. Med. Chem. 36: 3032-3034. PMID: 8411021
2. Barg, J., et al. 1995. Eur. J. Pharmacol. 287: 145-152. PMID: 8749028

Physical State :
Liquid
Solubility :
Soluble in ethanol, DMSO (~10 mg/ml), DMF (~10 mg/ml), and 1:2 solution of ethanol:PBS(pH7.2) (~8 mg/ml).
Storage :
Store at -20° C
Boiling Point :
544.48° C at 760 mmHg (Predicted)
Density :
0.93 g/cm3 (Predicted)
Refractive Index :
n20D 1.5 (Predicted)
Ki Data :
CB receptors: Ki= 34.4 nM; Cannabinoid CB1 receptor: Ki= 34.4 nM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5282273
MDL Number :
MFCD09878239
SMILES :
CCCCCC=CCC=CCC=CCC=CCCCCCC(=O)NCCO

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Certificate of Analysis

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