Dcun1D1/2 Antibody (A-11) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
raised against amino acids 71-233 mapping within an internal region of Dcun1D1 of human origin
Dcun1D1/2 Antibody (A-11) is recommended for detection of Dcun1D1 and Dcun1D2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
Dcun1D1/2 Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Dcun1D1/2 (A-11): sc-398218.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Dcun1D1, (Defective in cullin neddylation protein 1-like protein 1 or DCN1-like protein 1), also designated Rp42, Tes3 or squamous cell carcinoma-related oncogene (SCCRO) is involved in the malignant transformation of squamous cell lineage. Dcun1D1 regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues. Vascular endothelial growth factor-A (VEGF-A) is co-expressed with Dcun1D1, and the two function to induce angiogenesis. Overexpression of the Dcun1D1 gene is associated with invasive tumor progression and a poor outcome in non-small cell lung cancer, and low-level Dcun1D1 expression in adjacent benign lung tissue predicts an even worse survival rate. Dcun1D1 expression may be a marker of progressive dedifferentiation in squamous cell tumors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences