DAR-4M AM is a cell-permeable, photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM. Intracellularly releases DAR-4M by the action of esterases. Reacts with NO, in the presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. The fluorescence intensity of DAR-4M AM is not dependent on pH.
1. Kojima, H., et al. 2001. Anal. Chem. 73: 1967-1973. PMID: 11354477
See how others have used DAR-4M AM. Click on the entry to view the PubMed entry .
PMID: # 31067462 Coulombe, P. et al. 2019. Cell Rep. 27: 1769-1780.e4.
PMID: # 24599126 Patenaude, A. et al. 2014. Cancer Res. 74: 2402-11.
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