[D-Trp8]-gamma-MSHA selective agonist of the melanocortin 3 receptor (MC3-R)

[D-Trp8]-γ-MSH (CAS 321351-81-9)

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Application: A selective agonist of the melanocortin 3 receptor (MC3-R)
CAS Number: 321351-81-9
Molecular Weight: 1570.79
Molecular Formula: C74H99N21O16S
* Refer to Certificate of Analysis for lot specific data (including water content).
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[D-Trp8]-γ-MSH is a selective MC3-R (melanocortin 3 receptor) agonist (IC50 values are 6.7, 340 and 600 nM for human MC3-R, MC5-R and MC4-R receptors respectively). This compound also displays anti-inflammatory efficacy.

Appearance :
Lyophilized powder
Physical State :
Solid
Solubility :
Soluble in water (1 mg/mL).
Storage :
Desiccate at -20° C
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
MC3-R: EC5050 = 0.33 nM (human); MC3-R: IC50 = 6.7 nM (human); MC5-R: EC5050 = 82 nM (human); MC5-R: IC50 = 0.34 µM (human); MC4-R: IC50 = 0.6 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD09264730

Download SDS (MSDS)

Certificate of Analysis

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