D-saccharic acid calcium salt tetrahydrateAn inhibitor of beta-glucuronidase

D-saccharic acid calcium salt tetrahydrate (CAS 5793-89-5)

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Synonym: Calcium (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate tetrahydrate; Calcium Saccharate
Application: An inhibitor of beta-glucuronidase
CAS Number: 5793-89-5
Purity: ≥98%
Molecular Weight: 320.27
Molecular Formula: C6H8O8•Ca•4H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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D-saccharic acid calcium salt tetrahydrate is a nontoxic, natural compound. Derivative 1,4-GL increases detoxification of carcinogens and tumor promoters/progressors by inhibiting β-glucuronidase and preventing hydrolysis of their glucuronides.


References

Walaszek Z, Szemraj J, Narog M et al. Cancer Detect Prev. 21:178-90 (1997). Abou-Issa H, Moeschberger M, el-Masry W et al. Anticancer Res. 15:805-10 (1995).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in 5 M HCl.
Storage :
Store at room temperature
Melting Point :
>250° C
Boiling Point :
766.4° C at 760 mmHg (Predicted)
Density :
1.77 g/cm3 at 20° C
Refractive Index :
n20D ~1.64 (Predicted)
Optical Activity :
α20/D +20.5°±2°, c = 6 in 5 M HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16211545
Merck Index :
14: 1700
MDL Number :
MFCD00150704
EC Number :
227-334-1
Beilstein Registry :
3821334
SMILES :
[C@H]([C@@H]([C@@H](C(=O)[O-])O)O)([C@H](C(=O)[O-])O)O.O.O.O.O.[Ca+2]

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Certificate of Analysis

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D-saccharic acid calcium salt tetrahydrate  Product Citations

See how others have used D-saccharic acid calcium salt tetrahydrate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27671344  Kretschmer, SB. et al. 2017. Biochem. Pharmacol. 123: 52-62.

Citations 1 to 1 of 1 total
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